Hormones and Hormone Disruptors in the Environment Lecture Pix



Insect Hormonal System: Some pesticides work by interfering with hormonal systems, causing either accelerated or delayed development.


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How neurotoxic pesticides work. Under normal conditions a stimulated presynaptic cell (left) releases neurotransmitters from vesicles (wpe1.jpg (879 bytes)). The transmitters(wpe3.jpg (717 bytes)) float across the synaptic cleft (gap) and join with receptors on the postsynaptic cell (wpe4.jpg (911 bytes)). This excites the postsynaptic cell (wpe5.jpg (921 bytes)) and the postsynaptic cell produces an action potential.


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After the postsynaptic cell releases the neurotransmitters, they are reabsorbed by the presynaptic cell. Many antidepressants, such as Prozac, work at this level. Serotonin uptake inhibitors raise serotonin (a neurotransmitter) levels in the brain by interfering with the re-absorption. Serotonin levels then increase and the depression lifts.


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Cartoon depicting the movement of an action potential down an axon, release of neurotransmitters from vesicles, neurotransmitters hitching up to receptors on the postsynaptic cell, then depolarization of the postsynaptic cell and recycling of neurotransmitter by the presynaptic cell.


Pesticides such as malathion work as acetylcholinessterase inhibitors.



Early Embryology of Sexual Development is under the control of testosterone



General Structure of a Sheep Brain



White matter tracts inside the brain serves as a high-speed network to bypass surface grey matter.




Distribution of White and Grey Matter in the Brain



The Corpus Callosum


Presumptive male Presumptive female
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Fetal Alcohol Syndrome (FAS) Note very small corpus callosum.


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Hypothalamus- Differences in Neuron Density and other male-female differences